Professor of Chemical Engineering
Postdoctoral Fellowship, MIT
Ph.D., University of California, Berkeley
B.S., Rice University
Proteins are an incredible class of polymers – the precise sequence of amino acid monomers encodes its structure and transforms the simple polymer chain into a folded functional biomacromolecule. Among many amazing properties, protein biopolymers can (1) possess spectacular strength, (2) function as reliable machines, and (3) dynamically assemble and disassemble. Our research capitalizes on the diverse structure and function found in proteins and seeks to engineer complementary functionality into novel protein-based materials. Through genetic and synthetic modifications, we seek to gain responsive control of protein assembly and activity. By developing new protein-based materials, we strive to create new solutions to problems in biomedicine, biotechnology and synthetic biology.
Areas of concentration:
protein engineering, polymer science, complex coacervation, and chemical biology
Obermeyer, A.C.; Mills, C.E.; Dong, X-H.; Flores, R.J.; Olsen, B.D. Complex coacervation of supercharged proteins with polyelectrolytes. Soft Matter, 2016, 12, 3570-3581.
Obermeyer, A.C.; Olsen, B.D. Synthesis and application of protein-containing block copolymers. ACS Macro Letters, 2015, 4, 101-110.
Obermeyer, A.C.; Capehart, S.L.; Jarman, J.B.; Francis, M.B. Multivalent Viral Capsids with Internal Cargo for Fibrin Imaging, PLoS One, 2014, 9, e100678.
Obermeyer, A.C.; Jarman, J.B.; Francis, M.B. N-terminal modification of proteins with o-aminophenols, J. Am. Chem. Soc., 2014,136, 9572-9579.